從臨床檢體分離到的Streptococcus pneumoniae菌落，常呈黏稠且中央凹陷如火山口樣，主要是由下列何種特性所致？
Capsule and autolysin
C-substance and neuraminidase
Lipoteichoic acid and pneumolysin
Peptidoglycan and hyaluronidase
