丙酮酸去氫酶複合體(pyruvate dehydrogenase complex)，需數種維生素B，做為其輔酶。其中thiamine之需求是為了催化酵素複合體之那一個子反應？
puruvate decarboxylase
dihydrolipoyl transacetylase
dihydrolipoyl dehydrogenase
pyruvate carboxylase
