皮下注射mipomersen 能降低血中LDL 及lipoprotein(a),用於治療同合子家族性高膽固醇血症(homozygous familial hypercholesterolemia),其作用機制為何?
Apo-E 20-mer antisense oligonucleotide
antisense oligonucleotide target to cholesteryl ester transfer protein
HMG-CoA reductase inhibitor
Apo-B100 antisense oligonucleotide