內囊後區(posterior section of internal capsule)、腦幹(brainstem)及脊髓(spinal cord)之錐體系統(pyramidal system)出現核磁共振影像(MRI, T2)對稱性信號增強病灶,則最有可能的疾病是:
Hirayama disease
amyotrophic lateral sclerosis
spinocerebellar ataxia type III
progressive spinal muscular atrophy